NAD+ (100mg)

NAD⁺ (Nicotinamide Adenine Dinucleotide) Peptide

NAD⁺ (Nicotinamide Adenine Dinucleotide) is a pyridine nucleotide present in all living cells and a fundamental coenzyme in metabolic pathways. It functions primarily as a redox mediator, alternating between oxidized (NAD⁺) and reduced (NADH) states to facilitate electron transfer. This role places NAD⁺ at the center of energy production, mitochondrial activity, and cellular homeostasis.

In addition to its role in the electron transport chain, NAD⁺ is a substrate for several classes of enzymes, including sirtuins and poly(ADP-ribose) polymerases (PARPs). These enzymes utilize NAD⁺ in processes related to DNA repair, gene regulation, and protein modification, making it a molecule of broad experimental interest in genomic stability, cellular signaling, and metabolic regulation.

NAD⁺ is synthesized in cells through multiple pathways, including the de novo tryptophan pathway and salvage pathways utilizing precursors such as nicotinamide, nicotinic acid, nicotinamide riboside, and nicotinamide mononucleotide. Collectively, it is implicated in over 500 enzymatic reactions across diverse biological systems, reinforcing its importance as a cofactor in preclinical biochemical and molecular research.

Disclaimer: For laboratory research use only. Not for human consumption, diagnostic, or therapeutic purposes.